Methylation detection in Aneurinibacillus bacteria genome using nanopore sequencing

FCH/FEKT-J-24-8516
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Popis

The submitted project aims to develop a robust methylation detection pipeline utilizing ONT sequencing for in-depth analysis of Aneurinibacillus sp. methylomes. It is centered on a comparative analysis of two sequencing techniques (ONT and PacBio) for methylation detection. This serves as foundational knowledge to create a new neural network aimed at enhancing the accuracy of ONT. This endeavor will provide us with novel insights into the role of methylomes in bacteria cultivated under stress conditions.